CleanPlex Limb-Girdle Muscular Dystrophy NGS Panel • NUCLEUS BIOTECH

NUCLEUS BIOTECH • CleanPlex Limb-Girdle Muscular Dystrophy NGS Panel
The CleanPlex® Limb-Girdle Muscular Dystrophy NGS Panel for Illumina® or Ion Torrent™ is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 38 genes associated with Limb-Girdle Muscular Dystrophy. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads. This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries. You have the option to modify the existing content of this pre-designed panel. Please contact us for a quote.

Systemic cell therapy for muscular dystrophies

Limb Girdle Muscular Dystrophy Variant Curation Expert Panel - ClinGen

Novel compound heterozygous mutations in the TTN gene: elongation and truncation variants causing limb-girdle muscular dystrophy type 2J in a Han Chinese family

Frontiers Limb-Girdle Muscular Dystrophies (LGMDs): The Clinical Application of NGS Analysis, a Family Case Report

Complexity of skeletal muscle degeneration: multi-systems pathophysiology and organ crosstalk in dystrophinopathy

Genetic characterization of Limb Girdle Muscular Dystrophies and Pompe Disease in a large Argentine cohort - ScienceDirect

Limb-girdle muscular dystrophies — international collaborations for translational research

Diagnosis and discovery in limb-girdle muscular dystrophy

TRIM32 biallelic defects cause limb-girdle muscular dystrophy R8: identification of two novel mutations and investigation of genotype–phenotype correlation, Skeletal Muscle

Atamyo Therapeutics Submits CTA in Europe for Limb-Girdle Muscular Dystrophy Type 2C/R5 Gene Therapy

G-CSF supports long-term muscle regeneration in mouse models of muscular dystrophy

JCI Insight - Base editing repairs an SGCA mutation in human primary muscle stem cells

Limb Girdle Muscular Dystrophy Variant Curation Expert Panel - ClinGen

Gene-editing, immunological and iPSCs based therapeutics for muscular dystrophy - ScienceDirect

Molecular mechanisms of muscular dystrophies: old and new players