Dark space, Mass Effect Wiki

Dark space (or intergalactic space) is the name of the physical space between galaxies in the same way as interstellar space is the space between stars within a galaxy. Dark space is completely dark, as it contains little to no stars and makes up almost the entire volume of the universe, where galaxies are only small islands of light. The distance between two neighboring galaxies is in the order of several million light-years, while the diameter of the Milky Way's galactic disc is only about 100

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Dark space, Mass Effect Wiki